Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070335 | 0.88 | CNR1 (0.44) | ALDH1A1CNR2CNR1LMNANLRP3 | |
| SCHEMBL1464665 | 0.87 | RAB9A (0.50) | ALDH1A1CNR2CNR1RAB9ANPC1 | |
| SCHEMBL1465162 | 0.87 | NLRP3 (0.52) | ALDH1A1CNR2CNR1LMNANLRP3 | |
| SCHEMBL1464909 | 0.77 | CNR2 (0.57) | ALDH1A1CNR2CNR1NLRP3KMT2A | |
| SCHEMBL1464396 | 0.77 | CNR2 (0.63) | ALDH1A1CNR2CNR1LMNARAB9A | |
| SCHEMBL1464267 | 0.77 | CNR2 (0.51) | ALDH1A1CNR2CNR1LMNANLRP3 | |
| SCHEMBL4164059 | 0.76 | CNR2 (0.44) | ALDH1A1CNR2CNR1LMNALTC4S | |
| SCHEMBL12635879 | 0.75 | KMT2A (0.58) | ALDH1A1LMNANLRP3RAB9ANPC1 | |
| SCHEMBL3967415 | 0.73 | RAF1 (0.42) | ALDH1A1CNR2CNR1LMNANLRP3 | |
| SCHEMBL1464362 | 0.73 | CNR2 (0.57) | CNR2CNR1RAB9ANPC1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |