Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965799 | 0.88 | TLR4 (0.46) | TLR4ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL4077853 | 0.84 | TLR4 (0.55) | TLR4ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL8243047 | 0.81 | KMT2A (0.41) | TLR4ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL13883455 | 0.81 | TLR4 (0.45) | TLR4ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL8277704 | 0.80 | KMT2A (0.40) | TLR4ALDH1A1KMT2AGAAHSD17B10 | |
| SCHEMBL9968593 | 0.79 | KMT2A (0.39) | TLR4ALDH1A1KMT2AGAAHSD17B10 | |
| SCHEMBL30052789 | 0.78 | BRD4 (0.36) | TLR4KMT2AGAAMEN1 | |
| SCHEMBL27684837 | 0.78 | KMT2A (0.38) | TLR4KMT2AMAPTGAAPOLB | |
| SCHEMBL5659584 | 0.78 | TLR4 (0.50) | TLR4ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL1254599 | 0.78 | CYP2D6 (0.49) | ALDH1A1KMT2AGAAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885296-B | Preparation method of bromfenac sodium | 新发药业有限公司 | 2022-11-04 | — | — | CN | disclosed |
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |