Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967641 | 0.88 | TLR4 (0.46) | TLR4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4077853 | 0.84 | TLR4 (0.55) | TLR4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13883455 | 0.81 | TLR4 (0.45) | TLR4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5659584 | 0.78 | TLR4 (0.50) | TLR4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1617437 | 0.76 | TLR4 (0.49) | TLR4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8187713 | 0.76 | TLR4 (0.49) | TLR4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4080364 | 0.76 | ALDH1A1 (0.51) | TLR4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10642674 | 0.76 | TP53 (0.62) | TP53L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL7414681 | 0.76 | TP53 (0.62) | TP53L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL11674366 | 0.76 | ALDH1A1 (0.45) | TLR4MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |