Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962109 | 0.92 | PTGDR2 (0.39) | PTGDR2GNRHRKMT2AGAAMEN1 | |
| SCHEMBL3967113 | 0.90 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL3972653 | 0.88 | PTGDR2 (0.42) | PTGDR2GNRHRKMT2AGAAMEN1 | |
| SCHEMBL3962099 | 0.86 | PTGDR2 (0.40) | PTGDR2GAAPTGS2NPSR1PTGS1 | |
| SCHEMBL3962084 | 0.85 | PTGDR2 (0.39) | PTGDR2KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL3969463 | 0.85 | PTGDR2 (0.47) | PTGDR2KMT2AMEN1PTGS2MAPT | |
| SCHEMBL3968018 | 0.82 | PTGDR2 (0.39) | PTGDR2KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL3968970 | 0.82 | PTGDR2 (0.46) | PTGDR2KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL3967751 | 0.82 | PTGDR2 (0.39) | PTGDR2KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL3964681 | 0.81 | PTGDR2 (0.46) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |