Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965620 | 0.93 | PTGDR2 (0.54) | PTGDR2MMP2MMP12MMP13MMP14 | |
| SCHEMBL3968057 | 0.90 | PTGDR2 (0.59) | PTGDR2MMP2MMP12MMP13MMP14 | |
| SCHEMBL3962084 | 0.89 | PTGDR2 (0.39) | PTGDR2MEN1KMT2APTGS2 | |
| SCHEMBL3968970 | 0.88 | PTGDR2 (0.46) | PTGDR2MAPTMEN1KMT2APTGS2 | |
| SCHEMBL3962109 | 0.88 | PTGDR2 (0.39) | PTGDR2MAPTMEN1KMT2APTGS2 | |
| SCHEMBL3968018 | 0.86 | PTGDR2 (0.39) | PTGDR2MAPTMEN1KMT2APTGS2 | |
| SCHEMBL3972653 | 0.86 | PTGDR2 (0.42) | PTGDR2MAPTMEN1KMT2APTGS2 | |
| SCHEMBL3967751 | 0.86 | PTGDR2 (0.39) | PTGDR2MAPTMEN1KMT2APTGS2 | |
| SCHEMBL3962099 | 0.85 | PTGDR2 (0.40) | PTGDR2MAPTPTGS2 | |
| SCHEMBL3968252 | 0.85 | PTGDR2 (0.38) | PTGDR2MAPTMEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |