Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965951 | 0.74 | NPY5R (0.35) | NPC1RAB9ALMNAPOLBGAA | |
| SCHEMBL3956114 | 0.74 | KMT2A (0.42) | NPC1RAB9AEPHX1KMT2AMEN1 | |
| SCHEMBL2090645 | 0.71 | KMT2A (0.44) | NPC1RAB9AEPHX1LMNAKMT2A | |
| SCHEMBL3956362 | 0.71 | EPHX2 (0.41) | NPC1RAB9AEPHX1LMNAKMT2A | |
| SCHEMBL3966365 | 0.71 | TGM2 (0.43) | POLB | |
| SCHEMBL3966975 | 0.71 | HTT (0.39) | NPC1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL2092385 | 0.71 | KMT2A (0.43) | NPC1RAB9AEPHX1LMNAKMT2A | |
| SCHEMBL3959574 | 0.70 | CYP1A2 (0.46) | NPC1RAB9AEPHX1LMNAKMT2A | |
| SCHEMBL3959493 | 0.70 | NAMPT (0.44) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL21696977 | 0.65 | POLB (0.54) | HRH3NPC1RAB9AEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069346-A1 | ACETAMIDE AND CARBOXAMIDE DERIVATIVES OF AZAADAMANTANE AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008118743-A1 | ACETAMIDE AND CARBOXAMIDE DERIVATIVES OF AZAADAMANTANE AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | WO | disclosed |