Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966365 | 0.89 | TGM2 (0.43) | EPHX2TRPV1 | |
| SCHEMBL3958588 | 0.88 | RAB9A (0.41) | EPHX1RAB9AKMT2AALDH1A1HTT | |
| SCHEMBL3956114 | 0.85 | KMT2A (0.42) | EPHX1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3959574 | 0.80 | CYP1A2 (0.46) | EPHX2EPHX1RAB9ALMNAMEN1 | |
| SCHEMBL3959493 | 0.77 | NAMPT (0.44) | EPHX2RAB9ALMNAALDH1A1HTT | |
| SCHEMBL3966975 | 0.74 | HTT (0.39) | RAB9ALMNAMEN1KMT2AHTT | |
| SCHEMBL3965951 | 0.72 | NPY5R (0.35) | RAB9ALMNACNR1GAANPC1 | |
| SCHEMBL2092137 | 0.71 | TRPV1 (0.40) | EPHX2EPHX1CNR2RAB9ALMNA | |
| SCHEMBL3968445 | 0.71 | HRH3 (0.47) | EPHX1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL2090181 | 0.70 | TRPV1 (0.39) | EPHX2EPHX1CNR2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069346-A1 | ACETAMIDE AND CARBOXAMIDE DERIVATIVES OF AZAADAMANTANE AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008118743-A1 | ACETAMIDE AND CARBOXAMIDE DERIVATIVES OF AZAADAMANTANE AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | WO | disclosed |