Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 8/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.60 |
| ▸ | CCR8 | P51685 | 1/20 | 0.56 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964336 | 0.85 | NPC1 (0.54) | CHRM4CXCR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14132161 | 0.84 | F10 (0.67) | CHRM4CHRM2CHRM1CCR8NPC1 | |
| SCHEMBL3968898 | 0.83 | HPGD (0.63) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL3964755 | 0.83 | NPSR1 (0.53) | CHRM4CHRM2CHRM1NPC1RAB9A | |
| SCHEMBL3963855 | 0.82 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| Trifluoroacetic Acid SCHEMBL3968459 | 0.80 | F10 (0.62) | CHRM4CHRM2CHRM1CCR8 | |
| SCHEMBL3974111 | 0.80 | EPHX2 (0.49) | CHRM4NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL3971956 | 0.80 | F10 (0.73) | CHRM4 | |
| SCHEMBL29432103 | 0.79 | CHRM4 (1.00) | CHRM4CHRM2CHRM1 | |
| SCHEMBL12685848 | 0.78 | CHRM4 (0.67) | CHRM4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |