Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968540 | 0.91 | PTGDR2 (0.47) | PTGDR2RAPGEF4PTGDRPPME1HTR6 | |
| SCHEMBL3967967 | 0.91 | PTGDR2 (0.36) | PTGDR2RAPGEF4TRPV4DDR1PPME1 | |
| SCHEMBL13881877 | 0.88 | PTGDR2 (0.42) | PTGDR2RAPGEF4PTGDRDDR1PPARG | |
| SCHEMBL3969343 | 0.82 | PTGDR2 (0.39) | PTGDR2RAPGEF4PTGDRPPME1HTR6 | |
| SCHEMBL3963643 | 0.82 | PTGDR2 (0.42) | PTGDR2RAPGEF4PPME1HTR6 | |
| SCHEMBL4636233 | 0.75 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL3967117 | 0.75 | POLB (0.36) | PTGDR2RAPGEF4DDR1PPME1HTR6 | |
| SCHEMBL3968730 | 0.74 | PTGDR2 (0.42) | PTGDR2RAPGEF4PTGDRPPME1HTR6 | |
| SCHEMBL3327642 | 0.73 | ALDH1A1 (0.45) | PTGDR2PPARG | |
| SCHEMBL3974788 | 0.73 | PTGDR2 (0.46) | PTGDR2RAPGEF4PTGDRPPME1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044134-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |