Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396870 | 0.89 | ALDH1A1 (0.80) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL12177745 | 0.82 | ALDH1A1 (0.69) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL2318474 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL2325829 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1LMNATDP1IGF1R | |
| SCHEMBL1143469 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL398700 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL5229718 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL622653 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL28307056 | 0.79 | ALDH1A1 (0.66) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL10092801 | 0.78 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043855-B | Fluorescent probe for detecting water content in heavy water and application thereof | 安徽泽升科技有限公司 | 2023-02-10 | — | — | CN | claimed |
| CN-115043855-A | Fluorescent probe for detecting water content in heavy water and application thereof | 安徽泽升科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-110078659-A | A kind of isodextropimaric acid heterocycle acylhydrazone and its preparation method and application | 中国林业科学研究院林产化学工业研究所 | 2019-08-02 | — | — | CN | claimed |
| US-7495023-B2 | Thio semicarbazone and semicarbozone inhibitors of cysteine proteases and methods of their use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-02-24 | — | — | US | claimed |
| US-12421257-B2 | Compositions and methods for inhibiting group II intron RNA | YALE UNIVERSITY (US) | 2025-09-23 | — | — | US | disclosed |
| CN-118955466-A | Method for preparing unsaturated carbonyl compound by carbonyl-alkyne double decomposition reaction | 兰州大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-112469723-B | Cationically curable compositions with latent reducing agents exhibiting low cure temperatures | 汉高股份有限及两合公司 | 2024-09-20 | — | — | CN | disclosed |
| US-20240018169-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA | UNIV YALE (US) | 2024-01-18 | — | — | US | disclosed |
| CN-117384150-A | Thiazolidinones immunoproteasome inhibitor and its preparation method and pharmaceutical use | 中国医学科学院药物研究所 | 2024-01-12 | — | — | CN | disclosed |
| CN-117304921-A | Dual-emission fluorescent probe Cl, N-GQDs@EuBTC and preparation method and application thereof | 凯鑫森(上海)功能性薄膜产业股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-11739104-B2 | Compositions and methods for inhibiting group II intron RNA | YALE UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| CN-113480531-B | Piperonyl compound containing thiothiazolidine, preparation and application thereof | 中国农业大学 | 2023-05-05 | — | — | CN | disclosed |
| WO-2002015662-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |
| WO-2002017358-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |
| EP-1161438-A1 | 6-O-SUBSTITUTED MACROLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055168-A1 | 6-O-SUBSTITUTED MACROLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 2000-09-21 | — | — | WO | disclosed |
| WO-2000053313-A2 | LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES | ARQULE, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
| US-6054435-A | 6-O-substituted macrolides having antibacterial activity | ABBOTT LABORATORIES (US) | 2000-04-25 | — | — | US | disclosed |
| US-6046229-A | Polyaryl antitumor agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2000-04-04 | — | — | US | disclosed |
| US-3962284-A | 3-(5-ARYL-2-FURYL)-3-HYDROXYPROPIONIC ACIDS AND ETHYL ESTERS | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421257-B2 | Compositions and methods for inhibiting group II intron RNA | NSUN2, RBM22, RNGTT | KDM4E 3981/4885ALDH1A1 2984/4885LMNA 606/4885 |
| US-11739104-B2 | Compositions and methods for inhibiting group II intron RNA | NSUN2, RBM22, RNGTT | KDM4E 3981/4885ALDH1A1 2984/4885LMNA 606/4885 |
| US-20240018169-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA | NSUN2, RBM22, RNGTT | KDM4E 3981/4885ALDH1A1 2984/4885LMNA 606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.