Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757733 | 0.90 | KDM4E (0.56) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL396870 | 0.89 | ALDH1A1 (0.80) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL10092801 | 0.86 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL12177745 | 0.82 | ALDH1A1 (0.69) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL1143469 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL2325829 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL5229718 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL398700 | 0.80 | ALDH1A1 (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL397009 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL5737282 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1LMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3226858-B1 | IMIDAZOLE-BASED ANTIMICROBIAL AGENTS | PROCOMCURE BIOTECH GMBH (AT) | 2021-02-03 | — | — | EP | disclosed |
| CN-110483351-A | The method for preparing thioesters by oxo thioacetic acid compound | UNIV SCIENCE & TECHNOLOGY CHINA | 2019-11-22 | — | — | CN | disclosed |
| US-10456379-B2 | Imidazole-based antimicrobial agents | PROCOMCURE BIOTECH GMBH (AT) | 2019-10-29 | — | — | US | disclosed |
| US-10322110-B2 | Imidazole-based antimicrobial agents | PROCOMCURE BIOTECH GMBH (AT) | 2019-06-18 | — | — | US | disclosed |
| US-20170368032-A1 | Imidazole-Based Antimicrobial Agents | PROCOMCURE BIOTECH GMBH (AT) | 2017-12-28 | — | — | US | disclosed |
| US-20170334887-A1 | Imidazole-Based Antimicrobial Agents | PROCOMCURE BIOTECH GMBH (AT) | 2017-11-23 | — | — | US | disclosed |
| EP-3226858-A1 | IMIDAZOLE-BASED ANTIMICROBIAL AGENTS | Procomcure Biotech GmbH (AT) | 2017-10-11 | — | — | EP | disclosed |
| EP-2022794-B1 | FLUORESCENT COMPOUND AND LABELING AGENT COMPRISING THE SAME | UNIV KEIO (JP) | 2017-08-23 | — | — | EP | disclosed |
| US-9423396-B2 | Bodipy structure fluorescence probes for diverse biological applications | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-08-23 | — | — | US | disclosed |
| US-20160176859-A1 | High-Throughput Assay for Identifying Small Molecules that Modulate AMP-activated Protein Kinase (AMPK) | NORTH CAROLINA CENTRAL UNIVERSITY | 2016-06-23 | — | — | US | disclosed |
| US-20100130513-A1 | BENZIMIDAZOLES AND ANALOGS THEREOF AS ANTIVIRALS | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-7642265-B2 | Benzimidazoles and analogs thereof as antivirals | ISIS PHARMACEUTICALS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642265-B2 | Benzimidazoles and analogs thereof as antivirals | ISIS PHARMACEUTICALS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| EP-2022794-A1 | FLUORESCENT COMPOUND AND LABELING AGENT COMPRISING THE SAME | Keio University (JP) | 2009-02-11 | — | — | EP | disclosed |
| WO-2008005651-A2 | CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS | DECODE CHEMISTRY, INC. (US) | 2008-01-10 | — | — | WO | disclosed |
| WO-1993003719-A1 | ARYLALKYLETHER AND ARYLALKYLTHIOETHER INHIBITORS OF LIPOXYGENASE ENZYME ACTIVITY | ABBOTT LABORATORIES (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |
| US-4895867-A | 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0251380-A2 | 2- (5-phenyl-2-furanyl) imidazoles useful as cardiotonic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1988-01-07 | — | — | EP | disclosed |
| US-3946049-A | 5-PHENYL-2-FURAMIDOXIMES | MORTON-NORWICH PRODUCTS, INC. (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176859-A1 | High-Throughput Assay for Identifying Small Molecules that Modulate AMP-activated Protein Kinase (AMPK) | PRKAA1, PRKAG2, PRKAA2 | KDM4E 2052/4885ALDH1A1 1884/4885LMNA 3419/4885 |
| US-20100130513-A1 | BENZIMIDAZOLES AND ANALOGS THEREOF AS ANTIVIRALS | ZC3HAV1, NXF1, ZC3HAV1L | KDM4E 2466/4885ALDH1A1 2763/4885LMNA 1886/4885 |
| US-20170334887-A1 | Imidazole-Based Antimicrobial Agents | TLR5, NISCH, SLC11A2 | KDM4E 2893/4885ALDH1A1 1629/4885LMNA 4548/4885 |
| US-10456379-B2 | Imidazole-based antimicrobial agents | TLR5, NISCH, SLC11A2 | KDM4E 2893/4885ALDH1A1 1629/4885LMNA 4548/4885 |
| US-10322110-B2 | Imidazole-based antimicrobial agents | ARG1, SLC11A2, IKZF3 | KDM4E 1072/4885ALDH1A1 1211/4885LMNA 4362/4885 |
| US-20170368032-A1 | Imidazole-Based Antimicrobial Agents | TLR5, NISCH, SLC11A2 | KDM4E 2893/4885ALDH1A1 1629/4885LMNA 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.