SCHEMBL39701

SCHEMBL39701

O=C1C(Br)=CC=C2C1=Cc1cc(Br)ccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.42
PTPRC P08575 2/20 0.38
BCL2 P10415 2/20 0.37
MCL1 Q07820 1/20 0.37
TGM2 P21980 1/20 0.36
CES1 P23141 1/20 0.36
HSP90AA1 P07900 1/20 0.34
TLR9 Q9NR96 1/20 0.34
METAP1 P53582 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
TRPV1 Q8NER1 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP1A2 P05177 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP2 O95551 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28903176 0.86 S100A4 (0.42) S100A4PTPRCBCL2MCL1TGM2
SCHEMBL29651997 0.86 S100A4 (0.42) S100A4PTPRCBCL2MCL1TGM2
SCHEMBL28550903 0.83 TGM2 (0.34) TGM2CES1
SCHEMBL28915106 0.80 NPC1 (0.41) CA1CA2CA9L3MBTL1
SCHEMBL15554834 0.80 MEN1 (0.42) PTPRCL3MBTL1MAPK1TDP2PARP10
SCHEMBL827619 0.79 PTPRC (0.41) S100A4PTPRCCES1MAPK1TDP2
SCHEMBL27762245 0.79 PTPRC (0.46) S100A4PTPRCMCL1CES1CA1
SCHEMBL9262888 0.79 S100A4 (0.40) S100A4PTPRCBCL2MCL1TGM2
SCHEMBL28727378 0.75 S100A4 (0.37) S100A4PTPRCBCL2MCL1METAP1
SCHEMBL28404862 0.73 S100A4 (0.40) S100A4PTPRCBCL2MCL1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 538 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185057-A Preparation method of 9, 9-diaryl fluorene polymer spherulitic material 国之晖(苏州)科技有限公司 2024-06-14 CN claimed
CN-117753384-A Fluorenone polymer skin fiber membrane composite material and preparation method and application thereof 福州大学 2024-03-26 CN claimed
CN-111465589-B Compound having fluorene skeleton and method for producing same 帝人株式会社 2024-01-05 CN claimed
CN-117304919-A Organic fluorescent sensing array for selectively distinguishing and detecting sarin and preparation method thereof 中国科学院化学研究所 2023-12-29 CN claimed
CN-113742885-B Virtual simulation system based on SFX synthesis experiment 南京邮电大学 2023-10-20 CN claimed
CN-113277972-B Synthesis of hole transport material based on diphenylamine substituted carbazole fluorene hybridization and application of hole transport material in perovskite solar cell 云南大学 2023-06-16 CN claimed
CN-116199862-A Fluorene unit-based hole transport material, preparation method and perovskite battery 南京信息职业技术学院 2023-06-02 CN claimed
CN-112707882-B Spiro [ fluorene-9, 9' -xanthene ] nuclear hole transport material, preparation method and application thereof 合肥工业大学 2023-05-19 CN claimed
CN-115417975-A Fluorenyl polymer film with spherical crystal structure and preparation method and application thereof 南京工业大学 2022-12-02 CN claimed
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same TEIJIN LIMITED (JP) 2022-05-24 US claimed
CN-102120815-A Method for synthetizing white light polymer UNIV TAIYUAN TECHNOLOGY 2011-07-13 CN claimed
CN-101928276-A Method for synthesizing organic red light material UNIV TAIYUAN TECHNOLOGY 2010-12-29 CN claimed
CN-101624441-A Preparation method and application method of 4-9, 9-diaryl fluorene polymer material containing substituted radical UNIV NANJING POSTS & TELECOMM 2010-01-13 CN claimed
CN-101514160-A Method for preparing 2, 7-dibromo-4-nitrofluorenone UNIV SHANXI (CN) 2009-08-26 CN claimed
CN-100368366-C Process for preparing 2,7-dibromine fluorenes UNIV SHANXI (CN) 2008-02-13 CN claimed
CN-1907928-A Process for preparing 2,7-dibromine fluorenes UNIV SHANXI (CN) 2007-02-07 CN claimed
EP-1403239-B1 Production process of 2,7-dibromofluorenone JFE CHEMICAL CORP (JP) 2006-05-17 EP claimed
US-6977313-B2 Production process of 2,7-dibromofluorenone JFE CHEMICAL CORPORATION (JP) 2005-12-20 US claimed
EP-1403239-A1 Production process of 2,7-dibromofluorenone JFE Chemical Corporation (JP) 2004-03-31 EP claimed
US-20040059160-A1 Production process of 2,7-dibromofluorenone JFE CHEMICAL CORPORATION (JP) 2004-03-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same RFT1, AFF1, RER1 S100A4 4574/4885PTPRC 4872/4885BCL2 4047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.