Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396936 | 0.90 | THRB (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL419928 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5575871 | 0.83 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL17374783 | 0.83 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL28726211 | 0.82 | TSHR (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12544266 | 0.82 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL397026 | 0.82 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29011419 | 0.81 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL28396649 | 0.81 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL393525 | 0.80 | TSHR (0.40) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600820-B2 | Photocurable composition with high silicon content | CANON KABUSHIKI KAISHA (JP) | 2026-04-14 | — | — | US | claimed |
| US-20250368802-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY | CANON KK (JP) | 2025-12-04 | — | — | US | claimed |
| US-20240199816-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT | CANON KABUSHIKI KAISHA (JP) | 2024-06-20 | — | — | US | claimed |
| WO-2024123531-A1 | PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT | CANON KABUSHIKI KAISHA (JP) | 2024-06-13 | — | — | WO | claimed |
| US-20240159938-A1 | Compositions for Ophthalmologic Devices | JOHNSON & JOHNSON VISION CARE, INC. | 2024-05-16 | — | — | US | claimed |
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| US-11360241-B2 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2022-06-14 | — | — | US | claimed |
| EP-1945231-B1 | CONFORMABLE SOLVENT-BASED BANDAGE AND COATING MATERIAL | ROCHAL PARTNERS LLP (US) | 2021-11-10 | — | — | EP | claimed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | claimed |
| EP-3861039-A1 | HYDROGEL COMPOSITIONS | Ophtalmic Compagnie (FR) | 2021-08-11 | — | — | EP | claimed |
| US-20030162862-A1 | Contact lenses for extended wear (without surface treatment, coating-free), formed by reacting polyvinylpyrrolidone and (2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy) methylsilane, then curing | JOHNSON & JOHNSON VISION CARE, INC. | 2003-08-28 | — | — | US | claimed |
| US-20030122269-A1 | Method for forming on-site a coated optical article | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2003-07-03 | — | — | US | claimed |
| US-20030125498-A1 | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE, INC. | 2003-07-03 | — | — | US | claimed |
| WO-2003022322-A2 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-03-20 | — | — | WO | claimed |
| WO-2003022321-A2 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-03-20 | — | — | WO | claimed |
| US-6383502-B1 | Non-stinging coating composition | 3M INNOVATIVE PROPERTIES COMPANY | 2002-05-07 | — | — | US | claimed |
| US-6031059-A | POLYMERIZING A HYDROPHOBIC SILOXANE PREPOPLYMER AND A SILYLATED HYDROPHILIC MONOMER AND HYDROLYZING THE RESULTING POLYMER WHEREIN POLYMERIZING IS CARRIED OUT BY USING ONE OF HEAT POLYMERIZATION, ULTRAVIOLET LIGHT | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 2000-02-29 | — | — | US | claimed |
| US-5962548-A | SOFT CONTACT LENSES | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-0277555-B1 | COPOLYMERS WITH 0-NITROCARBINOL ESTER GROUPS, AND PROCESS FOR PREPARING TWO-LAYER RESISTS AND SEMICONDUCTOR DEVICES | BASF Aktiengesellschaft (DE) | 1992-04-08 | — | — | EP | claimed |
| US-4808682-A | BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600820-B2 | Photocurable composition with high silicon content | BIRC2, ACP1, IRS1 | TSHR 4173/4885THRB 4666/4885POLB 3409/4885 |
| US-20240159938-A1 | Compositions for Ophthalmologic Devices | PDE6D, CRYAB, PDE6H | TSHR 3951/4885THRB 4153/4885POLB 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.