Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783939 | 0.90 | TSHR (0.42) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL5702092 | 0.81 | TSHR (0.49) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL397026 | 0.81 | TSHR (0.45) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL393525 | 0.79 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL4454148 | 0.76 | THRB (0.46) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL229518 | 0.73 | TSHR (0.44) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL9558554 | 0.72 | TSHR (0.47) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL942089 | 0.72 | TSHR (0.47) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL1803423 | 0.72 | TSHR (0.42) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL5783932 | 0.71 | ALDH1A1 (0.33) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |