Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970668 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2SHBGRAB9AALDH1A1MAPT | |
| SCHEMBL3975568 | 0.78 | POLB (0.48) | SMN1; SMN2RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL3975567 | 0.78 | POLB (0.48) | SMN1; SMN2RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL3924409 | 0.77 | MAPT (0.57) | SMN1; SMN2RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL8543783 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9AALDH1A1MAPTMEN1 | |
| Water SCHEMBL8845490 | 0.75 | MAPT (0.56) | SMN1; SMN2RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL6124203 | 0.75 | G6PC1 (0.51) | SMN1; SMN2RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL8543996 | 0.74 | G6PC1 (0.60) | SMN1; SMN2RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL11984337 | 0.74 | G6PC1 (0.60) | SMN1; SMN2RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL3972358 | 0.74 | MAPT (0.57) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020003-A1 | Biphenyloxy-acids | AHR, ARNT, NR1H4 | SMN1; SMN2 4625/4885SHBG 257/4885RAB9A 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.