Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978937 | 0.83 | MAPT (0.50) | MAPTHTR2AL3MBTL1PKMKDM4E | |
| SCHEMBL3924409 | 0.82 | MAPT (0.57) | MAPTL3MBTL1KDM4EALDH1A1TDP1 | |
| Water SCHEMBL8845490 | 0.81 | MAPT (0.56) | MAPTL3MBTL1KDM4EALDH1A1TDP1 | |
| SCHEMBL16991889 | 0.80 | HTR2A (0.59) | MAPTHTR2APKMKDM4EALDH1A1 | |
| SCHEMBL3042373 | 0.78 | LMNA (0.69) | MAPTL3MBTL1KDM4EALDH1A1TDP1 | |
| Ether SCHEMBL8845483 | 0.77 | MAPT (0.50) | MAPTL3MBTL1PKMKDM4EALDH1A1 | |
| SCHEMBL29697785 | 0.77 | MAPT (0.56) | MAPTKDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL12326165 | 0.77 | MAPT (0.56) | MAPTKDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL3894418 | 0.74 | MAPT (0.62) | MAPTL3MBTL1PKMKDM4EALDH1A1 | |
| SCHEMBL3970664 | 0.74 | SMN1; SMN2 (0.45) | MAPTL3MBTL1PKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020003-A1 | Biphenyloxy-acids | AHR, ARNT, NR1H4 | MAPT 4702/4885HTR2A 402/4885L3MBTL1 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.