SCHEMBL3970904

SCHEMBL3970904

CN(C)CCCNS(=O)(=O)c1cc[c]cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.69
CA2 P00918 1/20 0.69
CA9 Q16790 1/20 0.69
ALOX15 P16050 1/20 0.68
ALDH1A1 P00352 8/20 0.55
KMT2A Q03164 3/20 0.55
NPSR1 Q6W5P4 2/20 0.54
TSHR P16473 1/20 0.54
GAA P10253 2/20 0.50
SFRP1 Q8N474 1/20 0.49
HDAC4 P56524 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
USP2 O75604 1/20 0.47
PKM P14618 3/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TMEM97 Q5BJF2 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
HTT P42858 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3971066 0.90 TSHR (0.66) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL6295282 0.84 USP2 (0.66) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL10816772 0.83 CA12 (0.73) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL18553819 0.82 CA12 (1.00) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL6291953 0.81 ALDH1A1 (0.55) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL4708382 0.81 LMNA (0.55) CA12CA2CA9ALDH1A1KMT2A
SCHEMBL6034675 0.81 CA12 (0.74) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL3322325 0.81 CA2 (0.74) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL31374287 0.81 CA2 (0.74) CA12CA2CA9ALOX15ALDH1A1
SCHEMBL1667391 0.81 CA12 (0.74) CA12CA2CA9ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7495040-B2 Actinic ray curable composition, image forming method using the same and ink-jet recording apparatus using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-02-24 US disclosed
US-20080012918-A1 Actinic Radiation Curable Ink-Jet Ink, And Image Forming Method And Ink-Jet Recording Apparatus Using The Same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-01-17 US disclosed
US-20050196697-A1 Actinic ray curable composition, image forming method using the same and ink-jet recording apparatus using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-09-08 US disclosed
US-20050165123-A1 Actinic ray curable composition, image forming method using the same and ink-jet recording apparatus using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-07-28 US disclosed
US-6855719-B1 Imidazo[1,2-A]pyridine and pyrazolo[2,3-A]pyridine derivatives ASTRAZENECA AB (SE) 2005-02-15 US disclosed
CN-1174981-C Imidazo [1, 2-A ] pyridine and pyrazolo [2, 3-A ] pyridine derivatives 2004-11-10 CN disclosed
EP-1214318-B1 IMIDAZO[1,2-A]PYRIDINE AND PYRAZOLO[2,3-A]PYRIDINE DERIVATIVES ASTRAZENECA AB (SE) 2003-10-08 EP disclosed
CN-1370163-A Imidazo [1,2-A] pyridine and pyrazolo [2,3-a] pyridine derivatives ASTRAZENECA AB (SE) 2002-09-18 CN disclosed
EP-1214318-A1 IMIDAZO[1,2-A]PYRIDINE AND PYRAZOLO[2,3-A]PYRIDINE DERIVATIVES AstraZeneca AB (SE) 2002-06-19 EP disclosed
WO-2001014375-A1 IMIDAZO[1,2-A]PYRIDINE AND PYRAZOLO[2,3-A]PYRIDINE DERIVATIVES ASTRAZENECA AB (SE) 2001-03-01 WO disclosed