Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720642 | 0.86 | ALDH1A1 (0.53) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL3976346 | 0.85 | ADORA1 (0.63) | MAPTMEN1KMT2AADORA1RXFP1 | |
| SCHEMBL3498934 | 0.76 | ALDH1A1 (0.50) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL29770865 | 0.75 | ALDH1A1 (0.44) | MAPTMEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL29770867 | 0.75 | ALDH1A1 (0.44) | MAPTMEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL3498006 | 0.72 | GRM6 (0.58) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL14876133 | 0.72 | ALDH1A1 (0.48) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL14875905 | 0.70 | ALDH1A1 (0.76) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL21930986 | 0.70 | ALDH1A1 (0.47) | MAPTMEN1KMT2ATP53KDM4E | |
| SCHEMBL3980249 | 0.70 | GRM6 (0.73) | MAPTMEN1KMT2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |