Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 9/20 | 0.73 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974628 | 0.92 | GRM6 (0.61) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3974612 | 0.92 | GRM6 (0.61) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3974186 | 0.92 | GRM6 (0.61) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3975104 | 0.91 | GRM6 (0.60) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3981712 | 0.89 | GRM6 (0.57) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL4087642 | 0.89 | GRM6 (0.57) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL4090650 | 0.82 | ADORA1 (0.77) | GRM6MAPTALDH1A1ADORA1MEN1 | |
| SCHEMBL4076833 | 0.79 | ADORA1 (0.66) | GRM6MAPTALDH1A1ADORA1MEN1 | |
| SCHEMBL4086503 | 0.79 | ADORA1 (0.72) | GRM6MAPTALDH1A1ADORA1MEN1 | |
| SCHEMBL3974619 | 0.78 | ADORA1 (0.67) | GRM6MAPTALDH1A1ADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |