Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.63 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971073 | 0.85 | MAPT (0.47) | ADORA1RXFP1ALDH1A1LMNAKMT2A | |
| SCHEMBL4091366 | 0.78 | ADORA1 (1.00) | ADORA1CNR2ALDH1A1KMT2ASRD5A2 | |
| SCHEMBL29770865 | 0.77 | ALDH1A1 (0.44) | CNR2RXFP1ALDH1A1LMNAKMT2A | |
| SCHEMBL29770867 | 0.77 | ALDH1A1 (0.44) | CNR2RXFP1ALDH1A1LMNAKMT2A | |
| SCHEMBL29720642 | 0.73 | ALDH1A1 (0.53) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL24095743 | 0.70 | RXFP1 (0.58) | RXFP1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL25354212 | 0.68 | RXFP1 (0.59) | RXFP1 | |
| SCHEMBL1013325 | 0.68 | RXFP1 (0.73) | RXFP1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL30042580 | 0.68 | RXFP1 (0.73) | RXFP1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL4090650 | 0.68 | ADORA1 (0.77) | ADORA1CNR2ALDH1A1KMT2ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |