Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17842262 | 0.86 | RAB9A (0.75) | SMN1; SMN2NPC1PKMEPHX2RAB9A | |
| SCHEMBL3971725 | 0.82 | CHRM4 (0.65) | SMN1; SMN2NPC1PKMEPHX2RAB9A | |
| SCHEMBL3964336 | 0.82 | NPC1 (0.54) | SMN1; SMN2NPC1PKMEPHX2RAB9A | |
| SCHEMBL3964755 | 0.82 | NPSR1 (0.53) | SMN1; SMN2NPC1PKMEPHX2RAB9A | |
| SCHEMBL8640087 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1PKMEPHX2RAB9A | |
| SCHEMBL3974111 | 0.82 | EPHX2 (0.49) | SMN1; SMN2NPC1PKMEPHX2RAB9A | |
| SCHEMBL3971956 | 0.82 | F10 (0.73) | F10 | |
| SCHEMBL3897958 | 0.81 | F10 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1F10 | |
| SCHEMBL3968898 | 0.81 | HPGD (0.63) | SMN1; SMN2NPC1PKMEPHX2RAB9A | |
| SCHEMBL7409264 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1PKMEPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |