Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 4/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964755 | 0.86 | NPSR1 (0.53) | EPHX2NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL3912286 | 0.84 | F10 (0.60) | EPHX2PKMGPR119F10 | |
| SCHEMBL3964336 | 0.84 | NPC1 (0.54) | EPHX2NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL3900481 | 0.84 | MGLL (0.55) | NPC1PKMRAB9AGPR119F10 | |
| SCHEMBL3249543 | 0.83 | MGLL (0.57) | GPR119MGLL | |
| SCHEMBL3900261 | 0.83 | F10 (0.55) | NPC1PKMRAB9ASMN1; SMN2F10 | |
| SCHEMBL3895250 | 0.82 | GPR119 (0.58) | EPHX2GPR119F10MGLL | |
| SCHEMBL3963855 | 0.82 | SMN1; SMN2 (0.57) | EPHX2NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL29502337 | 0.80 | GPR119 (0.50) | GPR119MGLL | |
| SCHEMBL29502295 | 0.80 | GPR119 (0.50) | GPR119MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |