Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971968 | 0.88 | MAPK1 (0.45) | CTSKCTSSPPARGPPARAMMP13 | |
| SCHEMBL4572150 | 0.82 | MTNR1A (0.49) | PTGDR2PTGDRHPGDPPARGPPARA | |
| SCHEMBL27730329 | 0.79 | CTSK (0.62) | CTSKCTSSPPARGPPARAACE | |
| SCHEMBL22042132 | 0.79 | CTSK (0.62) | CTSKCTSSPPARGPPARAACE | |
| SCHEMBL28108976 | 0.79 | CTSK (0.62) | CTSKCTSSPPARGPPARAACE | |
| SCHEMBL2754724 | 0.78 | CTSK (0.55) | CTSKCTSSACE | |
| SCHEMBL22526731 | 0.77 | ATM (0.40) | PTGDR2CTSKCTSSPTGIRFFAR1 | |
| SCHEMBL30169219 | 0.77 | ATM (0.40) | PTGDR2CTSKCTSSPTGIRFFAR1 | |
| SCHEMBL22526826 | 0.77 | PPARA (0.42) | CTSKCTSSPTGIRPTGFRPPARG | |
| SCHEMBL30169110 | 0.77 | CYSLTR2 (0.41) | CTSKCTSSPTGIRPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |