SCHEMBL3971988

SCHEMBL3971988

Cc1cc(C(F)(F)F)ccc1C(=O)Nc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 6/20 0.62
HPGD P15428 1/20 0.61
LMNA P02545 1/20 0.60
RAB9A P51151 2/20 0.58
NPC1 O15118 1/20 0.58
SORT1 Q99523 1/20 0.58
GPR27 Q9NS67 5/20 0.57
AVPR2 P30518 4/20 0.57
KCNK3 O14649 1/20 0.57
P2RX1 P51575 1/20 0.56
TP53 P04637 1/20 0.56
THRB P10828 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
HTT P42858 1/20 0.55
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11582566 0.85 SORT1 (0.61) RXFP1LMNARAB9ANPC1SORT1
SCHEMBL28468489 0.84 PTGS1 (0.69) RXFP1HPGDLMNARAB9ANPC1
SCHEMBL12544169 0.82 RXFP1 (0.88) RXFP1LMNAKCNK3P2RX1TP53
SCHEMBL28199416 0.82 P2RX1 (0.68) RXFP1HPGDLMNARAB9ANPC1
SCHEMBL6370502 0.81 SMN1; SMN2 (0.58) LMNARAB9ANPC1GPR27P2RX1
SCHEMBL4147334 0.81 GPR27 (0.72) HPGDRAB9ANPC1GPR27AVPR2
SCHEMBL31092079 0.81 SMN1; SMN2 (0.69) RXFP1LMNARAB9ANPC1GPR27
SCHEMBL4247052 0.80 NPC1 (0.86) LMNARAB9ANPC1KCNK3P2RX1
SCHEMBL11827383 0.79 SORT1 (0.58) RAB9ANPC1SORT1TP53SMN1; SMN2
SCHEMBL4797114 0.79 KDM4E (0.51) RXFP1HPGDLMNARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009048152-A2 UNSATURATED IMINE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-16 WO disclosed