Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.72 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | F12 | P00748 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501647 | 0.94 | AVPR2 (0.70) | GPR27AVPR2HPGDKMT2AMEN1 | |
| SCHEMBL19491370 | 0.91 | POLB (0.64) | GPR27AVPR2HPGDKMT2AMEN1 | |
| SCHEMBL19491395 | 0.87 | KMT2A (0.70) | GPR27AVPR2HPGDKMT2AMEN1 | |
| SCHEMBL14112955 | 0.86 | HPGD (0.69) | GPR27AVPR2HPGDKMT2AMEN1 | |
| SCHEMBL8770871 | 0.85 | ALDH1A1 (0.63) | GPR27AVPR2KMT2AMEN1TDP1 | |
| SCHEMBL14514566 | 0.85 | PLG (0.67) | GPR27AVPR2HPGDKMT2AMEN1 | |
| SCHEMBL8235539 | 0.85 | KMT2A (0.63) | GPR27AVPR2KMT2AMEN1POLB | |
| SCHEMBL5583049 | 0.85 | ALDH1A1 (0.69) | GPR27AVPR2HPGDKMT2AMEN1 | |
| SCHEMBL19350786 | 0.83 | GPR27 (0.74) | GPR27AVPR2HPGDKMT2AMEN1 | |
| SCHEMBL30192798 | 0.83 | TYK2 (0.67) | GPR27AVPR2KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
| EP-1277726-B1 | PROCESS FOR THE PREPARATION OF 2-HALOBENZOIC ACIDS | NIHON NOHYAKU CO LTD (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-7057067-B2 | Process for the preparation of 2-halobenzoic acids | NIHON NOHYAKU CO., LTD. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20030181759-A1 | Process for the preparation of 2-halobenzoic acids | NIHON NOHYAKU CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| US-6555663-B1 | Pharmaceuticals which are activated intracellularly by reaction with cellular electron carriers or free radicals to cause release of a free and active drug molecule | MILLS RANDELL LEE (US) | 2003-04-29 | — | — | US | disclosed |
| EP-1277726-A1 | PROCESS FOR THE PREPARATION OF 2-HALOBENZOIC ACIDS | Nihon Nohyaku Co., Ltd. (JP) | 2003-01-22 | — | — | EP | disclosed |
| EP-0414730-B1 | Chemical Compounds and pharmaceutical compositions capable of releasing a drug | MILLS RANDELL L (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5773592-A | COMPRISES A CHEMILUMINESCENT MOIETY, A PHOTOCHROMIC MOIETY AND A BIOLOGICALLY ACTIVE AGENT CAPABLE OF BEING RELEASED | MILLS RANDELL LEE (US) | 1998-06-30 | — | — | US | disclosed |
| US-5428163-A | Luminides; chemiluminescence; redox system, releasing free drug | MILLS RANDELL L (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0414730-A4 | LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS | — | 1993-06-16 | — | — | EP | disclosed |
| EP-0414730-A1 | LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS | Mills, Randell L. (US) | 1991-03-06 | — | — | EP | disclosed |
| WO-1989009833-A1 | LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS | MILLS RANDELL L (US) | 1989-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181759-A1 | Process for the preparation of 2-halobenzoic acids | HAO2, CBR1, AOC2 | GPR27 1245/4885AVPR2 1753/4885HPGD 1631/4885 |
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | PRMT5, CYC1, CBR3 | GPR27 4696/4885AVPR2 2571/4885HPGD 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.