SCHEMBL3972186

SCHEMBL3972186

CO[Si](OC)(c1ccccc1)c1ccc(Oc2ccccc2)cc1.CO[Si](OC)(c1ccccc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.56
TSHR P16473 1/20 0.50
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45
MAOA P21397 1/20 0.45
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
NLRP3 Q96P20 1/20 0.41
CA4 P22748 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1929693 1.00 LTA4H (0.56) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL18096779 0.98 LTA4H (0.58) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL706592 0.87 ESR1 (0.41) LTA4HTSHRNR1H2SMN1; SMN2MEN1
SCHEMBL49008 0.84 CA4 (0.41) LTA4HTSHRSMN1; SMN2MEN1KMT2A
SCHEMBL27596877 0.84 CA4 (0.41) LTA4HTSHRSMN1; SMN2MEN1KMT2A
SCHEMBL11588483 0.82 CA1 (0.41) LTA4HTSHRHPGDSMN1; SMN2MEN1
SCHEMBL27743669 0.82 CA4 (0.39) LTA4HTSHRSMN1; SMN2MEN1KMT2A
SCHEMBL21174882 0.81 LTA4H (0.48) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3109685 0.81 LTA4H (0.58) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL18105330 0.81 LTA4H (0.58) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019106-B1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same ROHM & HAAS (US) 2013-11-27 EP disclosed
EP-2019106-A1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same Rohm and Haas Company (US) 2009-01-28 EP disclosed