Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970372 | 0.99 | ACHE (0.48) | SIRT2ACHEADAM17 | |
| SCHEMBL4568768 | 0.76 | TLR4 (0.53) | SIRT2ADAM17 | |
| SCHEMBL4568904 | 0.76 | TLR4 (0.53) | SIRT2ADAM17 | |
| SCHEMBL4568767 | 0.76 | TLR4 (0.53) | SIRT2ADAM17 | |
| SCHEMBL4568818 | 0.76 | SIRT2 (0.52) | SIRT2ADAM17 | |
| SCHEMBL4256591 | 0.75 | GCK (0.49) | SIRT2ADAM17 | |
| SCHEMBL2207364 | 0.75 | BCHE (0.43) | SIRT2ADAM17 | |
| SCHEMBL4568813 | 0.75 | TLR4 (0.51) | — | |
| SCHEMBL4568749 | 0.74 | HPGD (0.51) | SIRT2ADAM17 | |
| SCHEMBL4568756 | 0.74 | HPGD (0.51) | SIRT2ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |