Sugi Predict

Sugi Predict / Compounds / SCHEMBL2207364

SCHEMBL2207364

SCHEMBL2207364

CCCN(C(=O)Oc1cccc(OCC2CCCCC2)c1)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 1/20 0.43
▸ SIRT2 Q8IXJ6 1/20 0.42
▸ ADAM17 P78536 1/20 0.42
▸ PARP10 Q53GL7 3/20 0.42
▸ PARP15 Q460N3 2/20 0.42
▸ SLC2A1 P11166 1/20 0.41
▸ TLR4 O00206 1/20 0.41
▸ TLR2 O60603 1/20 0.41
▸ KAT6A Q92794 1/20 0.41
▸ FFAR4 Q5NUL3 1/20 0.41
▸ FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2209466 0.99 BCHE (0.42) BCHESIRT2ADAM17PARP10PARP15
SCHEMBL2207367 0.79 SLC2A1 (0.42) SIRT2ADAM17PARP10PARP15SLC2A1
SCHEMBL2209469 0.77 SLC2A1 (0.41) SIRT2ADAM17PARP10PARP15SLC2A1
SCHEMBL28787293 0.77 BCHE (0.45) BCHE
SCHEMBL3972838 0.76 SLC2A1 (0.46) SIRT2ADAM17PARP10PARP15SLC2A1
SCHEMBL27889564 0.75 ALDH1A1 (0.45) BCHE
SCHEMBL3972837 0.75 SIRT2 (0.47) SIRT2ADAM17
SCHEMBL3970375 0.75 FFAR4 (0.45) SIRT2ADAM17PARP10PARP15SLC2A1
SCHEMBL2205654 0.75 ACHE (0.42) BCHE
SCHEMBL3970372 0.74 ACHE (0.48) SIRT2ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029708-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2024-07-09 — — US disclosed
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 — — US disclosed
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2021-03-18 — — US disclosed
US-10639286-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2020-05-05 — — US disclosed
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2019-06-20 — — US disclosed
US-10188615-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2019-01-29 — — US disclosed
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2018-06-28 — — US disclosed
EP-3210966-A1 ALKOXYPHENYLPROPYLAMINES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Acucela, Inc. (US) 2017-08-30 — — EP disclosed
US-9737496-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2017-08-22 — — US disclosed
US-20170049722-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2017-02-23 — — US disclosed
US-9458088-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2016-10-04 — — US disclosed
US-20150239836-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2015-08-27 — — US disclosed
US-20150239825-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2015-08-27 — — US disclosed
US-9079825-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2015-07-14 — — US disclosed
US-8993807-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2015-03-31 — — US disclosed
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-08-23 — — US disclosed
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-17 — — US disclosed
US-7982071-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2011-07-19 — — US disclosed
US-20090326074-A1 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2009-12-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029708-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20150239836-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER BCHE 1649/4885SIRT2 903/4885ADAM17 2404/4885
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20150239825-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20090326074-A1 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20170049722-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-10188615-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885
US-10639286-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER BCHE 1592/4885SIRT2 923/4885ADAM17 2449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.