SCHEMBL3972988

SCHEMBL3972988

CCO[Si](CCCNC(=O)c1ccncc1)(OCC)OCC

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.58
TSHR P16473 1/20 0.58
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GAA P10253 1/20 0.50
ALDH1A1 P00352 2/20 0.49
HDAC3 O15379 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC2 Q92769 1/20 0.49
NAMPT P43490 2/20 0.48
KMT2A Q03164 1/20 0.48
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29127798 0.87 NAAA (0.60) NAAANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13133224 0.85 NPC1 (0.54) NAAAL3MBTL1TSHRCYP1A2CYP2C19
SCHEMBL14190011 0.84 CYP1A2 (0.53) TSHRCYP1A2NPC1RAB9ASMN1; SMN2
SCHEMBL10774859 0.84 LMNA (0.54) NAAAL3MBTL1TSHRCYP1A2CYP2C19
SCHEMBL2045796 0.83 NPC1 (0.51) NAAAL3MBTL1TSHRNPC1RAB9A
SCHEMBL22249864 0.83 NPC1 (0.51) NAAAL3MBTL1TSHRNPC1RAB9A
SCHEMBL20774364 0.82 KMT2A (0.60) NPC1RAB9AALDH1A1HDAC3HDAC1
SCHEMBL9980885 0.82 NAAA (0.55) NAAAL3MBTL1NPC1RAB9ASMN1; SMN2
SCHEMBL3634350 0.81 NAAA (0.87) NAAAL3MBTL1TSHRCYP1A2CYP2C9
SCHEMBL28426668 0.81 NPC1 (0.52) NAAAL3MBTL1TSHRCYP2C9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115155663-A Preparation method of magnetic Wells-Dawson heteropoly acid composite material 山东交通学院 2022-10-11 CN disclosed
US-7579459-B2 Activator bound solid supports for nucleic acid synthesis via the phosphoramidite approach NGO NAM Q 2009-08-25 US disclosed
US-20070135626-A1 Activator bound solid supports for nucleic acid synthesis via the phosphoramidite approach CTGEN, INC (US) 2007-06-14 US disclosed