Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044554 | 0.86 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL13133224 | 0.86 | NPC1 (0.54) | NPC1RAB9AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL14190011 | 0.84 | CYP1A2 (0.53) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL10774859 | 0.84 | LMNA (0.54) | NPC1RAB9AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL29127798 | 0.84 | NAAA (0.60) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL13133125 | 0.84 | KMT2A (0.68) | NPC1RAB9AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL22249864 | 0.83 | NPC1 (0.51) | NPC1RAB9AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3972988 | 0.83 | NAAA (0.64) | NPC1RAB9AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL20774364 | 0.82 | KMT2A (0.60) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL9980885 | 0.82 | NAAA (0.55) | NPC1RAB9AALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381651-B1 | POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM | DOW CORNING TORAY CO LTD (JP) | 2011-06-29 | — | — | EP | disclosed |
| EP-1858982-B1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | DOW CORNING (US) | 2008-08-27 | — | — | EP | disclosed |
| US-20080182833-A1 | Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient | DOW CORNING CORPORATION | 2008-07-31 | — | — | US | disclosed |
| CN-101142279-A | Silicone emulsion, method of preparing same, and cosmetic ingredient | DOW CORNING (US) | 2008-03-12 | — | — | CN | disclosed |
| EP-1858982-A1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | Dow Corning Corporation (US) | 2007-11-28 | — | — | EP | disclosed |
| US-7300648-B2 | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | DOWECORNING TORAY SILICONE, CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| WO-2006102010-A1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | DOW CORNING CORPORATION (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20040138373-A1 | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | DOW TORAY CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1406575-A2 | POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS | Dow Corning Toray Silicone Co.,Ltd. Patent Department (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1381651-A1 | POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM | Dow Corning Toray Silicone Co.,Ltd. Patent Department (JP) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002094213-A2 | POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS | DOW CORNING TORAY SILICONE CO.,LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002088253-A1 | POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2002-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182833-A1 | Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient | SQLE, CUTA, SMOX | NPC1 864/4885RAB9A 4314/4885ALDH1A1 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.