Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.45 |
| ▸ | KDM6B | O15054 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AOC1 | P19801 | 6/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479238 | 0.90 | KDM4C (0.53) | LOXL2KDM4CKDM6BTDP1KDM4E | |
| SCHEMBL3931892 | 0.76 | KDM4C (0.48) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| Trifluoroacetic Acid SCHEMBL5015284 | 0.76 | TDP1 (0.56) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| SCHEMBL3880004 | 0.74 | KDM4C (0.50) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| SCHEMBL30465694 | 0.74 | KDM4C (0.51) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| SCHEMBL123203 | 0.74 | KDM4C (0.51) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| SCHEMBL6207070 | 0.73 | KDM4C (0.48) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| SCHEMBL7263236 | 0.73 | KDM4C (0.48) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| SCHEMBL7509912 | 0.73 | KDM4C (0.48) | KDM4CKDM6BTDP1KDM4EKDM4A | |
| Trifluoroacetic Acid SCHEMBL3614050 | 0.73 | LOXL2 (0.61) | LOXL2ALDH1A1L3MBTL1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054412-A2 | IMINO-IMIDAZO-PYRIDINE DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | Sanofi-Aventis (FR) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008014888-A2 | IMINO-IMIDAZO-PYRIDINE DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY | SANOFI-AVENTIS (FR) | 2008-02-07 | — | — | WO | disclosed |