Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.69 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.58 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30021086 | 1.00 | NOTUM (0.69) | NOTUMIDO1HSD17B3SLC22A12TUBB4A | |
| SCHEMBL698648 | 0.90 | NOTUM (0.62) | NOTUMIDO1HSD17B3CYP11B2KDM4E | |
| SCHEMBL23064005 | 0.87 | SLC22A12 (0.56) | NOTUMIDO1HSD17B3SLC22A12TUBB4A | |
| SCHEMBL4543419 | 0.87 | NOTUM (0.67) | NOTUMIDO1HSD17B3TRIM24ALDH1A1 | |
| SCHEMBL288802 | 0.85 | SLC22A12 (0.59) | NOTUMIDO1HSD17B3SLC22A12TUBB4A | |
| SCHEMBL12077343 | 0.83 | ADRB2 (0.55) | NOTUMIDO1HSD17B3SLC22A12TUBB4A | |
| SCHEMBL18921803 | 0.83 | ABHD6 (0.64) | NOTUMIDO1HSD17B3SLC22A12TUBB4A | |
| SCHEMBL19687695 | 0.83 | CYP11B1 (0.56) | SLC22A12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6072422 | 0.81 | NOTUM (0.73) | NOTUMCYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL423295 | 0.81 | NOTUM (1.00) | NOTUMCYP11B1CYP11B2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058525-A1 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, LLC | 2008-03-06 | — | — | US | claimed |
| WO-2004078874-A2 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | POLAROID CORPORATION (US) | 2004-09-16 | — | — | WO | claimed |
| US-20040171817-A1 | Novel dye complexes and use thereof in imaging members and methods | ZINK HOLDINGS LLC | 2004-09-02 | — | — | US | claimed |
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | US | disclosed |
| EP-3702354-B1 | COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY AND USE THEREOF | HAIHE BIOPHARMA CO LTD (CN) | 2024-05-22 | — | — | EP | disclosed |
| US-11866428-B2 | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LIMITED (GB) | 2024-01-09 | — | — | US | disclosed |
| CN-117143002-A | Preparation method of indolinyl acetone | 浙江工业大学 | 2023-12-01 | — | — | CN | disclosed |
| US-11807635-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2023-11-07 | — | — | US | disclosed |
| US-11807635-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | HAISCO PHARMACEUTICALS PTE. LTD. (SG) | 2023-11-07 | — | — | US | disclosed |
| CN-116768885-A | N 2 -substituted bicyclo-2-aminopyrimidine derivative, preparation method and medical application thereof | 浙江大学 | 2023-09-19 | — | — | CN | disclosed |
| EP-3573960-B1 | N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES | GENFIT (FR) | 2023-08-16 | — | — | EP | disclosed |
| EP-0742010-A2 | Benzoquinolin-3-ones to inhibit bone loss | ELI LILLY AND COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0733365-A2 | Use of benzoquinolin-3-ones for the treatment and prevention of prostatic cancer | ELI LILLY AND COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5550134-A | ADMINISTERING TO A MAMMAL FROM A SERIES OF BENZOQUINOLIN-3-ONE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| US-5538973-A | ANTIHISTAMINE, THROMBOXANE A2 ANTAGONIST | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0597112-A1 | NOVEL IMIDAZOLE DERIVATIVE, PHARMACEUTICAL USE THEREOF, AND INTERMEDIATE THEREFOR | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0227823-B1 | COLOR TRANSFER PHOTOGRAPHIC PROCESSES AND PRODUCTS | POLAROID CORPORATION (US) | 1989-03-22 | — | — | EP | disclosed |
| EP-0227823-A1 | COLOR TRANSFER PHOTOGRAPHIC PROCESSES AND PRODUCTS. | POLAROID CORP (US) | 1987-07-08 | — | — | EP | disclosed |
| WO-1987000307-A1 | COLOR TRANSFER PHOTOGRAPHIC PROCESSES AND PRODUCTS | POLAROID CORPORATION (US) | 1987-01-15 | — | — | WO | disclosed |
| US-4615966-A | Color transfer photographic processes and products with indole phthalein filter dyes | POLAROID CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807635-B2 | Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof | DPP4, DPP3, DPP9 | NOTUM 119/4885IDO1 837/4885HSD17B3 194/4885 |
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | NOTUM 3239/4885IDO1 2313/4885HSD17B3 1286/4885 |
| US-11866428-B2 | Bicyclic heterocycle compounds and their uses in therapy | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | NOTUM 3239/4885IDO1 2313/4885HSD17B3 1286/4885 |
| US-20080058525-A1 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | DBI, HSPE1, ABCB7 | NOTUM 2148/4885IDO1 991/4885HSD17B3 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.