SCHEMBL23064005

SCHEMBL23064005

CC(=O)C(=O)N1CCc2cc(Br)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.56
TUBB4A P04350 1/20 0.55
TUBB P07437 1/20 0.55
TUBA3C P0DPH7 1/20 0.55
TUBA1B P68363 1/20 0.55
TUBA4A P68366 1/20 0.55
TUBB4B P68371 1/20 0.55
TUBB3 Q13509 1/20 0.55
TUBB2A Q13885 1/20 0.55
TUBB8 Q3ZCM7 1/20 0.55
TUBA3E Q6PEY2 1/20 0.55
TUBA1A Q71U36 1/20 0.55
TUBA1C Q9BQE3 1/20 0.55
TUBB6 Q9BUF5 1/20 0.55
TUBB2B Q9BVA1 1/20 0.55
TUBB1 Q9H4B7 1/20 0.55
ABHD6 Q9BV23 1/20 0.54
NOTUM Q6P988 6/20 0.53
HSD17B3 P37058 2/20 0.49
IDO1 P14902 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30021086 0.87 NOTUM (0.69) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL397314 0.87 NOTUM (0.69) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL8904562 0.84 SLC22A12 (0.52) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL288802 0.82 SLC22A12 (0.59) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL8904564 0.80 TUBB4A (0.52) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL12077343 0.80 ADRB2 (0.55) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL19687695 0.80 CYP11B1 (0.56) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL18921803 0.80 ABHD6 (0.64) SLC22A12TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL698648 0.78 NOTUM (0.62) NOTUMHSD17B3IDO1PDK1PDK2
SCHEMBL18763042 0.77 SLC22A12 (0.58) SLC22A12TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2026-05-07 US disclosed
US-12522587-B2 Cancer treatments targeting cancer stem cells REMEDY PLAN, INC. (US) 2026-01-13 US disclosed
CN-119775198-A Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2025-04-08 CN disclosed
CN-112312899-B Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2024-11-22 CN disclosed
US-20220324842-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2022-10-13 US disclosed
EP-3787612-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS Remedy Plan, Inc. (US) 2021-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, MALT1, BCL6 SLC22A12 1955/4885TUBB4A 1654/4885TUBB 1635/4885
US-20220324842-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, CD47, GLI1 SLC22A12 3064/4885TUBB4A 3171/4885TUBB 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.