Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 16/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933800 | 0.78 | SSTR5 (0.44) | SSTR5KCNH2SSTR1 | |
| SCHEMBL2420778 | 0.78 | SSTR5 (0.54) | SSTR5KCNH2SSTR1 | |
| SCHEMBL2418190 | 0.78 | SSTR5 (0.61) | SSTR5KCNH2SSTR1 | |
| SCHEMBL3972896 | 0.76 | SSTR5 (0.43) | SSTR5KCNH2GPR119 | |
| SCHEMBL27753756 | 0.73 | SSTR5 (0.49) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4551486 | 0.72 | PTGS2 (0.35) | KCNH2PTGS2 | |
| SCHEMBL3976467 | 0.68 | KDM4E (0.51) | SSTR5SSTR1 | |
| SCHEMBL2421955 | 0.68 | SSTR5 (0.64) | SSTR5KCNH2 | |
| SCHEMBL4232088 | 0.68 | SSTR5 (0.44) | SSTR5KCNH2SSTR1 | |
| SCHEMBL4232220 | 0.68 | SSTR5 (0.46) | SSTR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054385-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008019967-A2 | PHENYL, PYRIDINE AND QUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-21 | — | — | WO | disclosed |