Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975612 | 0.88 | MAPT (0.43) | MAPTALDH1A1 | |
| SCHEMBL3973494 | 0.82 | IDH1 (0.39) | CNR2ALDH1A1HSD17B10 | |
| SCHEMBL23460345 | 0.80 | CNR2 (0.47) | CNR2MAPTPARK7ALDH1A1HSD17B10 | |
| SCHEMBL3972272 | 0.80 | CA1 (0.38) | ALDH1A1ACHE | |
| SCHEMBL3973824 | 0.80 | HTR2A (0.36) | CNR2ALDH1A1 | |
| SCHEMBL29427918 | 0.79 | CNR2 (0.49) | CNR2PARK7OPRK1KCNH2ACHE | |
| SCHEMBL25330974 | 0.79 | CNR2 (0.49) | CNR2PARK7OPRK1KCNH2ACHE | |
| SCHEMBL3973213 | 0.79 | HTR2A (0.42) | KCNH2 | |
| SCHEMBL24306468 | 0.78 | CNR2 (0.48) | CNR2PARK7ALDH1A1HSD17B10 | |
| SCHEMBL24305790 | 0.78 | CNR2 (0.43) | CNR2MAPTPARK7ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |