Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA6 | P23280 | 4/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973494 | 0.85 | IDH1 (0.39) | CA1CA2CA4CA6IDH1 | |
| SCHEMBL3973392 | 0.84 | CA1 (0.35) | CA1CA2CA4CA6PTPN1 | |
| SCHEMBL3971360 | 0.83 | ALDH1A1 (0.43) | BCHEACHEALDH1A1 | |
| SCHEMBL3973824 | 0.83 | HTR2A (0.36) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL3975612 | 0.82 | MAPT (0.43) | IDH1ALDH1A1GAA | |
| SCHEMBL3973213 | 0.82 | HTR2A (0.42) | — | |
| SCHEMBL3974894 | 0.81 | HTR2A (0.44) | ACHE | |
| SCHEMBL3972529 | 0.81 | MEN1 (0.45) | CA1CA2CA4CA6PTPN1 | |
| SCHEMBL3980428 | 0.80 | GAA (0.40) | IDH1GAA | |
| SCHEMBL3973411 | 0.80 | CNR2 (0.45) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |