Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972272 | 0.85 | CA1 (0.38) | IDH1ALDH1A1GAACA1CA2 | |
| SCHEMBL3973824 | 0.85 | HTR2A (0.36) | CNR2ALDH1A1SMN1; SMN2TDP1CA1 | |
| SCHEMBL3973213 | 0.84 | HTR2A (0.42) | MAPK1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL3971360 | 0.83 | ALDH1A1 (0.43) | CNR2ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL3974894 | 0.83 | HTR2A (0.44) | MAPK1POLBTSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL4084541 | 0.82 | SYK (0.45) | MAPK1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3973411 | 0.82 | CNR2 (0.45) | CNR2ALDH1A1HSD17B10 | |
| SCHEMBL3973392 | 0.81 | CA1 (0.35) | CA1CA2CA4CA6 | |
| SCHEMBL3972529 | 0.80 | MEN1 (0.45) | POLBTDP1CA1CA2CA4 | |
| SCHEMBL3979633 | 0.80 | POLB (0.43) | ALDH1A1KDM4EPOLBSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |