Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971360 | 0.88 | ALDH1A1 (0.43) | KDRCNR2ALDH1A1LY96 | |
| SCHEMBL3973494 | 0.85 | IDH1 (0.39) | CNR2CA1CA2CA4CA6 | |
| SCHEMBL3972272 | 0.83 | CA1 (0.38) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL3975184 | 0.82 | CA1 (0.32) | CA1CA2CA4CA6 | |
| SCHEMBL3974167 | 0.82 | BCHE (0.39) | DRD2CNR2 | |
| SCHEMBL3973213 | 0.81 | HTR2A (0.42) | HTR2AKDRDRD2SMN1; SMN2 | |
| SCHEMBL3974894 | 0.81 | HTR2A (0.44) | HTR2AKDRDRD2SMN1; SMN2 | |
| SCHEMBL4084541 | 0.80 | SYK (0.45) | KDRGSK3BSMN1; SMN2ALDH1A1 | |
| SCHEMBL3973411 | 0.80 | CNR2 (0.45) | CNR2ALDH1A1 | |
| SCHEMBL3973392 | 0.79 | CA1 (0.35) | CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |