Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975153 | 0.85 | NPC1 (0.38) | KMT2ANPC1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL3978577 | 0.84 | OXER1 (0.43) | NPC1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3972624 | 0.77 | POLB (0.55) | KMT2ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9959370 | 0.73 | KMT2A (0.56) | KMT2ANPC1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL3975404 | 0.72 | CREBBP (0.45) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL3973960 | 0.72 | KDM4E (0.38) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3990809 | 0.72 | CNR2 (0.60) | CNR1CNR2 | |
| SCHEMBL2260028 | 0.72 | NPSR1 (0.41) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL3973488 | 0.72 | NR4A2 (0.51) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL3993831 | 0.72 | NTRK1 (0.42) | KMT2ANPC1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |