Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404285 | 0.77 | ALDH1A1 (0.46) | NPSR1ALDH1A1HTTKMT2ANPC1 | |
| SCHEMBL2916195 | 0.72 | HPGD (0.37) | ALDH1A1KMT2ARAB9ATSHRTDP1 | |
| SCHEMBL13252246 | 0.71 | ALDH1A1 (0.44) | NPSR1ALDH1A1HTTKMT2ANPC1 | |
| SCHEMBL3425238 | 0.71 | ALDH1A1 (0.44) | NPSR1ALDH1A1HTTKMT2ANPC1 | |
| Bromide SCHEMBL6570241 | 0.71 | HPGD (0.36) | ALDH1A1KMT2ARAB9ATSHRTDP1 | |
| SCHEMBL11346026 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL11346022 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KMT2APOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL11794697 | 0.70 | MEN1 (0.35) | NPSR1ALDH1A1KMT2ANPC1POLB | |
| SCHEMBL196635 | 0.69 | KMT2A (0.49) | NPSR1ALDH1A1HTTKMT2ANPC1 | |
| SCHEMBL22733801 | 0.68 | ALDH1A1 (0.37) | NPSR1ALDH1A1HTTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051910-A1 | COMPOUNDS HAVING ACTIVITY IN INCREASING ION TRANSPORT BY MUTANT-CFTR AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-23 | — | — | WO | disclosed |