Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751630 | 0.84 | CA2 (0.41) | ALDH1A1ALOX15KMT2APOLBKEAP1 | |
| SCHEMBL2301619 | 0.83 | TDP1 (0.44) | ALDH1A1ALOX15KEAP1NFE2L2TDP1 | |
| SCHEMBL11692296 | 0.82 | KEAP1 (0.41) | ALDH1A1ALOX15L3MBTL1TSHRNPC1 | |
| SCHEMBL15939364 | 0.82 | KEAP1 (0.41) | L3MBTL1KMT2AKEAP1NFE2L2 | |
| SCHEMBL17352821 | 0.82 | TSHR (0.44) | ALDH1A1ALOX15TSHRKMT2ANPC1 | |
| SCHEMBL1520473 | 0.80 | ALDH1A1 (0.43) | ALDH1A1ALOX15NPSR1TSHRKMT2A | |
| SCHEMBL2558482 | 0.80 | MAPT (0.45) | ALDH1A1NPSR1L3MBTL1KMT2ANPC1 | |
| SCHEMBL6172326 | 0.78 | KEAP1 (0.57) | KEAP1NFE2L2 | |
| SCHEMBL13252246 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NPSR1L3MBTL1TSHRKMT2A | |
| SCHEMBL3973751 | 0.77 | NPSR1 (0.36) | ALDH1A1ALOX15NPSR1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428342-B1 | Stable thiol-ene compositions | LOCTITE IRELAND LTD (IE) | 1997-01-15 | — | — | EP | claimed |
| US-5358976-A | Curable; stabilization by addition of a non-acidic N-nitroso compound | LOCTITE (IRELAND) LIMITED (IE) | 1994-10-25 | — | — | US | claimed |
| US-4016216-A | Stabilizing 2,3-dichloro-1,3-butadiene with certain N-nitrosoaniline compounds | TOYO SODA MANUFACTURING CO., LTD. (JA) | 1977-04-05 | — | — | US | claimed |
| US-4013580-A | Method of preventing formation of popcorn chloroprene polymer | TOYO SODA MANUFACTURING CO., LTD. (JA) | 1977-03-22 | — | — | US | claimed |
| US-9802980-B2 | Method for producing pyrazoles, novel pyrazoles and applications thereof | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-10-31 | — | — | US | disclosed |
| EP-2291167-B1 | RADICAL POLYMERISATION INHIBITORS FOR LIGHT-CURABLE DENTAL MATERIALS | DENTSPLY DETREY GMBH (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-20150368295-A1 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-12-24 | — | — | US | disclosed |
| US-8507570-B2 | Radical polymerization inhibitors for light-curable dental materials | DENTSPLY INTERNATIONAL INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120142804-A1 | Radical Polymerization Inhibitors for Light-Curable Dental Materials | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20110196056-A1 | RADICAL POLYMERIZATION INHIBITORS FOR LIGHT-CURABLE DENTAL MATERIALS | BLACKWELL GORDON | 2011-08-11 | — | — | US | disclosed |
| EP-2291167-A2 | RADICAL POLYMERISATION INHIBITORS FOR LIGHT-CURABLE DENTAL MATERIALS | Dentsply DeTrey GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009135678-A2 | RADICAL POLYMERISATION INHIBITORS FOR LIGHT-CURABLE DENTAL MATERIALS | DENTSPLY DETREY GMBH (DE) | 2009-11-12 | — | — | WO | disclosed |
| EP-0428342-B1 | Stable thiol-ene compositions | LOCTITE IRELAND LTD (IE) | 1997-01-15 | — | — | EP | disclosed |
| US-5358976-A | Curable; stabilization by addition of a non-acidic N-nitroso compound | LOCTITE (IRELAND) LIMITED (IE) | 1994-10-25 | — | — | US | disclosed |
| EP-0484054-A1 | Stabilised thiol-ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0428342-A2 | Stable thiol-ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1991-05-22 | — | — | EP | disclosed |
| US-4016216-A | Stabilizing 2,3-dichloro-1,3-butadiene with certain N-nitrosoaniline compounds | TOYO SODA MANUFACTURING CO., LTD. (JA) | 1977-04-05 | — | — | US | disclosed |
| US-4013580-A | Method of preventing formation of popcorn chloroprene polymer | TOYO SODA MANUFACTURING CO., LTD. (JA) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196056-A1 | RADICAL POLYMERIZATION INHIBITORS FOR LIGHT-CURABLE DENTAL MATERIALS | MAP1LC3A, MAP1LC3B, MAP1LC3C | ALDH1A1 1093/4885ALOX15 1793/4885NPSR1 4803/4885 |
| US-20120142804-A1 | Radical Polymerization Inhibitors for Light-Curable Dental Materials | EPN1, MAP1LC3C, MAP1LC3A | ALDH1A1 663/4885ALOX15 1469/4885NPSR1 4830/4885 |
| US-20150368295-A1 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | NDUFS7, NDUFS3, UQCRB | ALDH1A1 155/4885ALOX15 1182/4885NPSR1 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.