Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.61 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451376 | 0.92 | CNR1 (0.67) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL5339340 | 0.90 | CNR1 (0.64) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL5339345 | 0.90 | CNR1 (0.64) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL2185711 | 0.88 | CNR1 (0.65) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL28980108 | 0.87 | CNR1 (0.64) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL28980254 | 0.87 | CNR1 (0.64) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL6416042 | 0.87 | EPHX2 (0.68) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL4624712 | 0.87 | EPHX2 (0.68) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL4624706 | 0.87 | EPHX2 (0.68) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| Sulfuric Acid SCHEMBL29001433 | 0.86 | CNR1 (0.60) | CNR1ALDH1A1HPGDTRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034802-B2 | Friction reduction fluids | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| EP-2054486-A2 | FRICTION REDUCTION FLUIDS | Services Pétroliers Schlumberger (FR) | 2009-05-06 | — | — | EP | disclosed |
| US-20080064614-A1 | Formulated to reduce drag while flowing into oil well and propagating fracture but to enhance drag when acid component reacts with formation or its fluids | SCHLUMBERGER TECHNOLOGY CORPORATION | 2008-03-13 | — | — | US | disclosed |
| WO-2008020388-A2 | FRICTION REDUCTION FLUIDS | SCHLUMBERGER CANADA LIMITED (CA) | 2008-02-21 | — | — | WO | disclosed |