SCHEMBL3973787

SCHEMBL3973787

Cc1cc(C)c(C(C)(C)c2c(C)cc(C)cc2O)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.46
SELP P16109 1/20 0.46
SELE P16581 1/20 0.46
ACHE P22303 1/20 0.46
ESR1 P03372 2/20 0.41
TP53 P04637 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 7/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
POLB P06746 2/20 0.39
CA2 P00918 1/20 0.39
TYR P14679 1/20 0.39
KDM4E B2RXH2 4/20 0.38
MAPT P10636 4/20 0.38
GAA P10253 2/20 0.38
LMNA P02545 1/20 0.38
TRPA1 O75762 1/20 0.37
APEX1 P27695 1/20 0.34
MPI P34949 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394948 0.86 SELL (0.46) SELLSELPSELEACHEESR1
SCHEMBL9742612 0.77 SELL (0.52) SELLSELPSELEACHEESR1
SCHEMBL1455423 0.76 CNR1 (0.39) SELLSELPSELEACHEESR1
SCHEMBL16658450 0.76 ESR1 (0.42) SELLSELPSELEACHEESR1
SCHEMBL205747 0.74 ACHE (0.72) SELLSELPSELEACHEESR1
SCHEMBL1058389 0.73 KDM4E (0.37) SELLSELPSELEACHEPOLB
SCHEMBL13868088 0.73 L3MBTL1 (0.36) SELLSELPSELEACHETP53
SCHEMBL18535704 0.72 ALDH1A1 (0.39) SELLSELPSELEACHETP53
SCHEMBL2886053 0.72 CYP3A4 (0.48) ACHEESR1TDP1ALDH1A1SMN1; SMN2
SCHEMBL1109746 0.72 ALDH1A1 (0.39) SELLSELPSELEACHETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
EP-1361241-B1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU KOSAN CO (JP) 2005-08-24 EP disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1178068-B1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU KOSAN CO (JP) 2005-05-18 EP disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed
EP-1361241-A1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-11-12 EP disclosed
EP-0896975-B1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN CO (JP) 2003-06-04 EP disclosed
EP-1288242-A2 Polycarbonate, and molding and electrophotograpic photoreceptor prepared therefrom Idemitsu Kosan Co., Ltd. (JP) 2003-03-05 EP disclosed
EP-1178068-A1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-02-06 EP disclosed
US-6136521-A POLYORGANOSILOXANE-CONTAINING POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2000-10-24 US disclosed
EP-0896975-A1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1999-02-17 EP disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed