Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251355 | 0.90 | TSHR (0.58) | TSHRMAPK1TDP1CA1CA2 | |
| SCHEMBL16712984 | 0.89 | TSHR (0.56) | TSHRMAPK1TDP1CA1CA2 | |
| SCHEMBL5992360 | 0.82 | VCAM1 (0.60) | TSHRMAPK1TDP1MAPTMEN1 | |
| SCHEMBL29398960 | 0.82 | TSHR (1.00) | TSHRMAPK1TDP1CA1CA2 | |
| SCHEMBL487215 | 0.82 | TSHR (1.00) | TSHRMAPK1TDP1CA1CA2 | |
| SCHEMBL2461199 | 0.80 | VCAM1 (0.58) | TSHRMAPK1TDP1MAPTMEN1 | |
| Fluoride SCHEMBL4646971 | 0.80 | TSHR (0.96) | TSHRMAPK1TDP1CA1CA2 | |
| SCHEMBL10521677 | 0.80 | TSHR (0.67) | TSHRMAPK1TDP1CA1CA2 | |
| SCHEMBL2859245 | 0.80 | HSD17B10 (0.69) | TSHRMAPK1TDP1CA1CA2 | |
| SCHEMBL10945034 | 0.79 | ERN1 (0.50) | TSHRMAPK1TDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727781-B1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL SCIENT IND RES (IN) | 2009-05-06 | — | — | EP | claimed |
| EP-1727781-A1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | Council of Scientific and Industrial Research (IN) | 2006-12-06 | — | — | EP | claimed |
| WO-2005063679-A1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | claimed |
| US-5276132-A | Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-01-04 | — | — | US | claimed |
| EP-1727781-B1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL SCIENT IND RES (IN) | 2009-05-06 | — | — | EP | disclosed |
| EP-1727781-B1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL SCIENT IND RES (IN) | 2009-05-06 | — | — | EP | disclosed |
| EP-1727781-A1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | Council of Scientific and Industrial Research (IN) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005063679-A1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |
| US-6835854-B1 | Oxidation of 3,3'-dichloro 4,4'-diaminobiphenyl (DCB), ammonolysis of the resulting 3,3'-dichloro-4,4'-dinitrobiphenyl (DCDNB) and reduction of 3,3'-diamino-4,4'-dinitrobiphenyl and treating with an alkali | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-12-28 | — | — | US | disclosed |
| EP-0503918-B1 | Liquid crystal aligning agent and aligning agent-applied liquid crystal display device | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5286887-A | Polymers of metal-complexes of phthalocyanines, porphrins, and crypt and crown compounds; solvent-insoluble oxidation catalysts | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-02-15 | — | — | US | disclosed |
| US-5276132-A | Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-01-04 | — | — | US | disclosed |
| WO-1993006150-A1 | POLYMERS OF MACROCYCLIC METAL CHELATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-04-01 | — | — | WO | disclosed |
| EP-0503918-A1 | Liquid crystal aligning agent and aligning agent-applied liquid crystal display device | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-H728-H | Aryloxy p-benzidine compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1990-02-06 | — | — | US | disclosed |