Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | ICMT | O60725 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974083 | 1.00 | SOAT2 (0.53) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL8410623 | 0.95 | ALDH1A1 (0.47) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL8410625 | 0.95 | ALDH1A1 (0.47) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL19732872 | 0.89 | SOAT2 (0.56) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL19751312 | 0.89 | SOAT2 (0.56) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL30271651 | 0.89 | SOAT2 (0.56) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL21065463 | 0.85 | SOAT2 (0.59) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL21065474 | 0.85 | SOAT2 (0.59) | SOAT2SOAT1ICMTALBALDH1A1 | |
| SCHEMBL28242834 | 0.83 | MAPT (0.51) | ALDH1A1HTTLMNAMAPTTHRB | |
| SCHEMBL334254 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482362-B2 | Substituted-4-quinolones | THE SECRETARY OF STATE FOR DEFENSE (GB) | 2009-01-27 | — | — | US | disclosed |
| US-7371779-B2 | Synergistic compositions of N-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENSE SCIENCE AND TECHNOLOGY (GB) | 2008-05-13 | — | — | US | disclosed |
| EP-1349550-B1 | SUBSTITUTED-4-QUINOLONES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | SECR DEFENCE (GB) | 2006-06-14 | — | — | EP | disclosed |
| EP-1404315-B1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | UNIV NOTTINGHAM (GB) | 2004-11-03 | — | — | EP | disclosed |
| US-20040198978-A1 | Synergistic compositions of n-acylhomoserine lactones and 4-quinolones | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2004-10-07 | — | — | US | disclosed |
| US-20040082579-A1 | Immunosuppressant | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2004-04-29 | — | — | US | disclosed |
| EP-1404315-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2004-04-07 | — | — | EP | disclosed |
| EP-1349550-A1 | SUBSTITUTED-4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-10-08 | — | — | EP | disclosed |
| WO-2003004017-A1 | SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2003-01-16 | — | — | WO | disclosed |
| WO-2002047686-A1 | SUBSTITUTED-4-QUINOLONES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082579-A1 | Immunosuppressant | CCR6, CCR1, CCR8 | SOAT2 724/4885SOAT1 369/4885ICMT 1897/4885 |
| US-20040198978-A1 | Synergistic compositions of n-acylhomoserine lactones and 4-quinolones | CBR3, CBR1, CNR1 | SOAT2 392/4885SOAT1 387/4885ICMT 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.