Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410623 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNATHRB | |
| SCHEMBL3974081 | 0.95 | SOAT2 (0.53) | ALDH1A1MAPTLMNATHRBICMT | |
| SCHEMBL3974083 | 0.95 | SOAT2 (0.53) | ALDH1A1MAPTLMNATHRBICMT | |
| SCHEMBL28242834 | 0.85 | MAPT (0.51) | ALDH1A1SMN1; SMN2MAPTLMNATHRB | |
| SCHEMBL19751312 | 0.83 | SOAT2 (0.56) | ALDH1A1ICMTALBSOAT2SOAT1 | |
| SCHEMBL19732872 | 0.83 | SOAT2 (0.56) | ALDH1A1ICMTALBSOAT2SOAT1 | |
| SCHEMBL30271651 | 0.83 | SOAT2 (0.56) | ALDH1A1ICMTALBSOAT2SOAT1 | |
| SCHEMBL334253 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNATHRB | |
| SCHEMBL334254 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNATHRB | |
| SCHEMBL28243621 | 0.81 | LMNA (0.48) | ALDH1A1SMN1; SMN2MAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |