Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylbutanoic Acid SCHEMBL5522186 | 0.90 | FFAR3 (0.53) | TDP1ALDH1A1FFAR3CACNA2D1CACNB3 | |
| 3-Methylbutanoic Acid SCHEMBL5511012 | 0.89 | FFAR3 (0.59) | TDP1ALDH1A1FFAR3CACNA2D1CACNB3 | |
| 3-Methylbutanoic Acid SCHEMBL609818 | 0.86 | TDP1 (0.58) | TDP1ALDH1A1FFAR3CACNA2D1CACNB3 | |
| 3-Methylbutanoic Acid SCHEMBL3217564 | 0.86 | TDP1 (0.58) | TDP1ALDH1A1CACNA2D1CACNB3CACNA1C | |
| 3-Methylbutanoic Acid SCHEMBL467274 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1FFAR3CACNA2D1CACNB3 | |
| 3-Methylbutanoic Acid SCHEMBL43436 | 0.86 | — | — | |
| 3-Methylbutanoic Acid SCHEMBL1331498 | 0.86 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL28106970 | 0.84 | ALDH1A1 (0.74) | TDP1ALDH1A1FFAR3CACNA2D1CACNB3 | |
| Methyl Isobutyl Ketone SCHEMBL15772913 | 0.84 | ALDH1A1 (0.74) | TDP1ALDH1A1FFAR3CACNA2D1CACNB3 | |
| 3-Methylbutanoic Acid SCHEMBL2303256 | 0.83 | TDP1 (0.48) | TDP1ALDH1A1FFAR3CACNA2D1CACNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053424-A9 | CRYSTALLINE SALT OF MONTELUKAST | INKE SA (ES) | 2009-08-06 | — | — | WO | claimed |
| US-20090111849-A1 | CRYSTALLINE SALT OF MONTELUKAST | INKE, SA (ES) | 2009-04-30 | — | — | US | claimed |
| WO-2009053424-A1 | CRYSTALLINE SALT OF MONTELUKAST | INKE, S.A. (ES) | 2009-04-30 | — | — | WO | claimed |
| EP-2053043-A1 | Crystalline salt of montelukast | INKE, S.A. (ES) | 2009-04-29 | — | — | EP | claimed |
| EP-1030869-A1 | POLYURETHANE BINDING AGENTS HAVING A LOW CONTENT OF HIGHLY VOLATILE MONOMERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024486-A1 | POLYURETHANE BINDING AGENTS HAVING A LOW CONTENT OF HIGHLY VOLATILE MONOMERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111849-A1 | CRYSTALLINE SALT OF MONTELUKAST | CMA1, CYSLTR1, SYMPK | TDP1 4775/4885ALDH1A1 4271/4885FFAR3 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.