Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956443 | 0.81 | ENPP2 (0.45) | ERN1ALDH1A1ABCG2CA1CA2 | |
| SCHEMBL21979585 | 0.81 | ENPP2 (0.45) | ERN1ALDH1A1ABCG2CA1CA2 | |
| SCHEMBL269268 | 0.79 | ALDH1A1 (0.56) | ERN1ALDH1A1ABCG2SRCTLR2 | |
| SCHEMBL31474876 | 0.79 | ALDH1A1 (0.56) | ERN1ALDH1A1ABCG2SRCTLR2 | |
| SCHEMBL23882160 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1TLR2TLR1TLR6 | |
| SCHEMBL31694460 | 0.79 | ERN1 (0.50) | ERN1ALDH1A1TLR2TLR1TLR6 | |
| SCHEMBL29683824 | 0.78 | ERN1 (0.59) | ERN1ALDH1A1ABCG2SRCTLR2 | |
| SCHEMBL3658867 | 0.78 | ERN1 (0.59) | ERN1ALDH1A1ABCG2SRCTLR2 | |
| SCHEMBL1796152 | 0.77 | TUBB4A (0.49) | ERN1ALDH1A1ABCG2CA1CA2 | |
| SCHEMBL29521638 | 0.77 | ALDH1A1 (0.50) | ERN1ALDH1A1ABCG2SRCTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |