Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978001 | 0.84 | OPRM1 (0.42) | OPRL1OPRM1OPRD1OPRK1SLC6A9 | |
| SCHEMBL3976441 | 0.82 | CYP2D6 (0.45) | OPRL1OPRM1OPRD1OPRK1SLC6A9 | |
| SCHEMBL3976532 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3979332 | 0.71 | CYP2D6 (0.41) | OPRL1OPRM1OPRD1OPRK1SLC6A9 | |
| SCHEMBL3975405 | 0.70 | GRIN2B (0.44) | OPRK1CYP2C9CYP2C19 | |
| SCHEMBL4183999 | 0.70 | OPRM1 (0.50) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL4176734 | 0.70 | OPRM1 (0.50) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL1716774 | 0.70 | OPRM1 (0.50) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL4187954 | 0.69 | CYP2D6 (0.45) | OPRL1OPRM1OPRD1OPRK1HSD11B1 | |
| SCHEMBL4182073 | 0.69 | CYP2D6 (0.45) | OPRL1OPRM1OPRD1OPRK1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563805-B2 | 7-[3-Amino-3,4-dimethylpyrrolidine-1-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acid: quinoline bactericide; broad spectrum, strong antibacterial activity for Grampositive/-negative including multiple resistant cocci; side effect reductcion; drug design | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-21 | — | — | US | disclosed |
| US-20060264428-A1 | Tri-, tetra-substituted-3-aminopyrrolidine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264428-A1 | Tri-, tetra-substituted-3-aminopyrrolidine derivative | QTRT1, RRS1, LAS1L | OPRL1 354/4885OPRM1 606/4885OPRD1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.