SCHEMBL3974447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28254795	0.78	HRH3 (0.50)	HRH3NOTUMKDM4EALDH1A1MAPK1
	SCHEMBL28046310	0.78	NCOA3 (0.56)	HRH3NOTUMKDM4EALDH1A1MAPK1
	SCHEMBL12313261	0.77	POLB (0.50)	KDM4EALDH1A1MAPK1MAPTMAOA
	SCHEMBL3665773	0.76	NOTUM (0.53)	HRH3NOTUMKDM4EALDH1A1MAPK1
	SCHEMBL6779647	0.73	NOTUM (0.50)	HRH3NOTUMKDM4EALDH1A1MAPK1
	SCHEMBL30437871	0.73	NLRP3 (0.55)	HRH3NOTUMKDM4EALDH1A1MAPK1
	SCHEMBL11337325	0.73	NOTUM (0.63)	NOTUMKDM4EALDH1A1MAPK1MEN1
	SCHEMBL7425604	0.73	NOTUM (0.50)	HRH3NOTUMKDM4EALDH1A1MAPK1
	SCHEMBL16506222	0.72	NOTUM (0.57)	NOTUMKDM4EALDH1A1MAPK1NLRP3
	SCHEMBL23667579	0.72	KDM4E (0.57)	HRH3NOTUMKDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.